How good is the evidence available in child protection?

Translating evidence into practice: how good is good enough?

The birth of the evidence-based medicine (EBM) movement in the early 1990s generated a greater interest in measuring the extent to which scientific knowledge was appropriately applied to therapeutic decisions. Investigators sought to challenge the widespread belief that only a minority of treatments provided to patients were based upon the best available scientific evidence. In 1995 Ellis and c...

Transgenerational epigenetic inheritance in mammals: how good is the evidence?

Epigenetics plays an important role in orchestrating key biologic processes. Epigenetic marks, including DNA methylation, histones, chromatin structure, and noncoding RNAs, are modified throughout life in response to environmental and behavioral influences. With each new generation, DNA methylation patterns are erased in gametes and reset after fertilization, probably to prevent these epigeneti...

Contribution of Micronutrients Intake to the Risk of Multiple Sclerosis: Is the Available Evidence Convincing?

Why and How Is Compassion Necessary to Provide Good Healthcare? Comments From an Academic Physician; Comment on “Why and How Is Compassion Necessary to Provide Good Quality Healthcare?”

This is a short commentary to the editorial issued by Marianna Fotaki, entitled: “Why and how is compassion necessary to provide good quality healthcare.” It introduces the necessity of a more cognitive approach to explore further the determinants of behavior towards compassionate care. It raises questions about the importance of training towards a more patient-care and values driven healthcare...

How good is the evidence linking breastfeeding and intelligence?

BACKGROUND We conducted a critical review of the many studies that have tried to determine whether breastfeeding has a beneficial effect on intellect. DESIGN/METHODS By searching Medline and the references of selected articles, we identified publications that evaluated the association between breastfeeding and cognitive outcomes. We then appraised and described each study according to 8 princ...